A Smarter Approach to Long-Term Vision Health
NADefense was founded to bring clarity and structure to an important question: What can adults do to support their vision as they age?
Why NAD Matters in Ocular Health
The retina and optic nerve are among the most energy-demanding tissues in the body. As we age, cellular energy production naturally declines. One key molecule involved in that process is NAD (nicotinamide adenine dinucleotide).
NAD decline is widely discussed in the longevity space. However, it is not talked about enough in the context of vision health.
Emerging research has explored how supporting cellular energy and mitochondrial function may play a role in maintaining retinal health. While supplements are not treatments, many people want responsible options that complement their existing care.
NADefense was built around that idea.
From Clinical Experience to Daily Simplicity
Over decades of practice, Dr. Fishman reviewed research on NAD production, retinal ganglion cells, and nutritional support strategies. He began recommending certain nutrients individually to appropriate patients as part of broader wellness discussions.
For more than 30 years, Dr. Fishman practiced ophthalmology and saw the same pattern again and again. People did not just want prescriptions. They wanted to understand what was happening inside their eyes. They wanted to be proactive. They wanted something simple they could do daily to support long-term eye health.
NADefense was created to make that possible.
Can I take one thing that puts this together?
The question patients asked most oftenSight Guard was formulated to simplify that approach into one daily capsule designed to support cellular energy, antioxidant balance, and age-related vision wellness.*
Evidence-Informed Formulation
NADefense focuses on ingredients that have been studied in human research related to ocular health and aging. Sight Guard includes:
We carefully review clinical research and published trials when designing formulations. Where evidence is strong, we align with it. Where research is still emerging, we acknowledge that openly.
We do not position supplements as replacements for prescribed therapy. We believe in supporting your routine, not replacing it.
What Makes NADefense Different
Ophthalmologist-founded
Built from decades of real-world patient care.
Focused on cellular energy and optic nerve support
We look beyond surface-level nutrition and consider mitochondrial health as part of aging.
Transparent and responsible
We publish ingredient amounts clearly and avoid exaggerated claims.
Manufactured in the USA
Produced in a GMP-certified facility.
Designed for everyday people
Simple. Structured. One daily capsule.
Who NADefense Is For
NADefense is designed for adults who:
- Want to support long-term vision health
- Are interested in NAD and cellular energy
- Have a family history of age-related eye concerns
- Prefer a research-aware supplement approach
- Want something that complements their doctor's care
Our products are not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any supplement.
Our Mission
NADefense exists to elevate the conversation around age-related vision support.
As research into NAD, mitochondrial function, and ocular health continues to evolve, we are committed to staying grounded in science, transparency, and safety.
We believe vision wellness deserves the same thoughtful approach seen in other areas of longevity science.
Daily Defense for Lifelong Vision.
Explore Sight Guard